As per CIOMS, signal is “Information that arises from one or multiple sources (including observations and experiments) which suggests a new potentially causal association, or a new aspect of a known association, between an intervention and an event or set of related events, either adverse or beneficial, that is judged …
Definition: Immunization error-related reactions are AEFI that is caused by inappropriate vaccine handling, prescribing or administration and thus by its nature is preventable These reactions are preventable and the main focus in these reactions are on the nature of the error rather than on the biologic process giving rise to …
The Lancet said the early-stage trials suggested the Sputnik-V vaccine produced a response in a component of the immune system known as T cells. Scientists have been scrutinising the role played by T cells in battling coronavirus infection, with recent findings showing these cells may provide longer-term protection than antibodies. …
Despite remarkable success of immunization programmes on a global perspective, vaccines are neither 100% efficacious nor 100% effective. Therefore, vaccination failure, i.e. occurrence of a specific disease in an individual despite previous vaccination, may occur. Vaccination failure may be due to actual vaccine failure or failure to vaccinate appropriately. A. …
Detection and reporting of AEFI Parents of immunized infants/children, health workers at immunization facilities and staff of accident and emergency rooms in hospitals are most likely to recognize or detect AEFIs when they first occur. Reportable AEFIs: Serious AEFIs Signals and events associated with a newly introduced vaccine AEFI’s caused …
Vaccination is one of the great public health achievements of human history. Vaccines used in national immunization programmes (NIPs) are considered safe and effective when used correctly. Vaccines are, however, not risk-free and adverse events will occasionally occur following vaccination. Although most adverse events are minor (e.g. redness at injection …
