New Zealand Medicines and Medical Devices Safety Authority (Medsafe) has informed health-care professionals of the risk of impaired renal function associated with the use of ibuprofen.
Ibuprofen is widely used for the temporary relief of pain or inflammation and is available over the counter and with a prescription.
The Centre for Adverse Reactions Monitoring (CARM) has received five reports of patients with acute kidney injury associated with ibuprofen in which dehydration was considered a possible contributing factor. The risk of impaired renal function is increased in patients who are dehydrated, especially children and adolescents.
Authority recommended “When prescribing ibuprofen, health-care professionals should consider whether the patient is adequately hydrated”.
Source: Prescriber Update, Medsafe
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