Paracetamol, also known as acetaminophen and APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain relief. It is often sold in combination with other medications, such as in many cold medications.
Paracetamol is an effective, simple analgesic that is well tolerated by adults and children at therapeutic doses. In many countries it is available without prescription. Unfortunately, its ready availability is associated with episodes of poisoning.
Recently, Medsafe Newzeland has received cases of serious adverse events related to medication errors associated with prescribing, dispensing and communication to caregivers in children. Medicines Adverse Reactions Committee (MARC) discussed a report of “acute hepatic failure” in a child given a suspected paracetamol overdose.
It is recommended that Paracetamol should be used only for approved indications (Pain, Fever). The correct dose should be calculated using body weight. Health-care professionals should prescribe paracetamol precisely and dispense diligently.
As per drug information, the maximum amount of paracetamol for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more paracetamol could cause damage to your liver. Paracetamol should not be taken by consumer who drink more than three alcoholic beverages per day without first talking to doctor.
The first signs of an paracetamol overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes. Seek emergency medical care if you experience these symptoms.
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